When it comes to health supplements, glucosamine and chondroitin are among the most popular. Just how popular are they? According to one estimate, about one in five Americans takes glucosamine and one in 10 takes chondroitin. The cost of these and other non-vitamin supplements and herbal remedies is close to 15 billion dollars per year. So you’d think they must be highly effective. And yet, that’s not so clear.
They are touted not only as arthritis pain relievers but also as treatments to prevent joint disease. Yet, a number of past studies have come to mixed conclusions — some small studies found that people felt better taking glucosamine and/or chondroitin, but at least as many have found no benefit. A 2010 analysis of multiple studies (called a meta-analysis) found that among more than 3,800 people with osteoarthritis of the knee or hip, treatment with glucosamine, chondroitin, or the combination was no better than placebo. The case for these supplements protecting joint health or preventing arthritis is similarly weak.